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Brandýs nad Orlicí is situated at an altitude of 305 m at the river Tichá Orlice (Stille Adler), about 11 km northwest of the district town Ústí nad Orlicí. The town once was a major seat of the Bohemian (or Moravian) Brethren. Between 1622 and 1625 the theologian and educator Johann Amos Comenius (Jan Amos Komenský) (1592–1670) worked here on his book The Labyrinth of the World and the Paradise of the Heart (Labirynt swěta a lusthauz srdce, dedication 1623, published 1631 and 1663).

The castle [near right, no.156: background right] on the hill overlooking the town dates back to the 13th century. It was renovated in 1547 but was abandoned in the 17th century. Today only ruins remain.

The parish church of the Ascension of Jesus (kostel Nanebevstoupení Pána Ježíše) [near left, no.2452: background right; and right, no:156: centre left] was built 1778–1787 in Baroque style.